DelveInsight’s ‘Spasticity – Market Insights, Epidemiology, and Market Forecast–2032’ report delivers an in-depth understanding of spasticity historical and forecasted epidemiology as well as the spasticity market trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
Spasticity Overview
Spasticity is a condition in which there is an abnormal increase in muscle tone or muscle stiffness, which might interfere with movement and speech or be associated with discomfort or pain. Spasticity may be associated with spinal cord injury, multiple sclerosis, cerebral palsy, stroke, brain or head trauma, amyotrophic lateral sclerosis, hereditary spastic paraplegias, and metabolic diseases such as adrenoleukodystrophy, phenylketonuria, and Krabbe disease. Symptoms may include hypertonicity (increased muscle tone), clonus (a series of rapid muscle contractions), exaggerated deep tendon reflexes, muscle spasms, scissoring (involuntary crossing of the legs), and fixed joints (contractures). The degree of spasticity varies from mild muscle stiffness to severe, painful, and uncontrollable muscle spasms. Spasticity can interfere with rehabilitation in patients with certain disorders and often interferes with daily activities.
Spasticity Epidemiology Insights
In 2021, the total cases of spasticity were ~7,871,000 in the 7MM which is expected to increase by 2032.
The United States, in 2021, accounted for the highest number of cases of spasticity (~4,756,000 cases). These cases are expected to increase by the year 2032.
In 2021, Japan accounted for ~823,000 cases of spasticity, which was approximately 10% of the total spasticity cases in 7MM.
The total number of mild, moderate, and severe spasticity cases in the 7MM was ~1,504,000; ~2,424,000; and ~1,582,000 in 2021.
In 2021, the total number of spasticity cases due to cerebral palsy, multiple sclerosis, post-stroke, traumatic brain injury, and spinal cord injury were ~533,000; ~499,000; ~689,000; ~472,000; and ~98,000 respectively in the EU5.
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The Report Covers the Spasticity Epidemiology Segmented by:
Spasticity prevalent cases
Spasticity diagnosed cases
Spasticity treatment cases
Spasticity incident cases
Spasticity Market Outlook
Spasticity affects a patient’s independence in activities of daily living such as hygiene, dressing, self-comfort, ambulation, and sleep. Later it may lead to significant pain, contractures, joint subluxations or dislocations, peripheral neuropathy, and pressure ulcers. Therefore, treating this condition is imperative to improve the quality of life and minimize medical complications. Conversely, spasticity can help patients transfer, stand, ambulate, and maintain muscle bulk.
Various treatments are available for controlling spasticity; nonmedical treatments, including physical, occupational, and complementary and alternative medicine, are effective adjuncts to mainstream oral agents and interventional therapies. While each therapy is efficacious in treating spasticity, the treatments also come with adverse effects. In general, oral agents are more inexpensive in the short term and easier to use, but they have unwanted systemic effects, which can outweigh the potential benefits they may provide. At the same time, these systemic drugs may be better for patients with generalized spasticity.
On the other hand, interventional therapies pose the problem of procedural errors, difficulty finding a trained provider to perform the procedure, and further complications. However, it may provide greater control of spasticity with fewer systemic side effects if patients are compliant and can tolerate the procedures. Although there are effective treatment options for spasticity, there is currently no cure.
Key Companies Working in the Spasticity Market
Ipsen Biopharmaceuticals, Inc
RVL Pharmaceuticals
Merz Pharmaceuticals
Allergan, Inc
Jazz Pharmaceuticals
Metacel Pharmaceuticals
And many others
Spasticity Therapies Covered and Analyzed in the Report:
Arbaclofen ER
IPN10200
MYOBLOC
Botulinum toxin
SPARC0921
Hyaluronidase
Learn more about the Key Companies and Emerging Therapies in the Spasticity Market
Table of Contents
Key Insights
Spasticity Introduction
Executive Summary of Spasticity –
Disease Background and Overview
Epidemiology and patient population
Spasticity Emerging Therapies
Market Access and Reimbursement of Therapies
Market Drivers
Market Barriers
Appendix
Report Methodology
DelveInsight Capabilities
Disclaimer
Learn about the detailed offerings of the report @ Spasticity Market Outlook
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